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Literature summary extracted from

  • Adeboye, P.; Bettiga, M.; Olsson, L.
    ALD5, PAD1, ATF1 and ATF2 facilitate the catabolism of coniferyl aldehyde, ferulic acid and p-coumaric acid in Saccharomyces cerevisiae (2017), Sci. Rep., 7, 42635 .
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
4.1.1.102 degradation expression of aldehyde dehydrogenase Ald5, phenylacrylic acid decarboxylase Pad1, and alcohol acetyltransferases Atf1 and Atf2 increases conversion of coniferyl aldehyde, ferulic acid and p-coumaric acid. Combined overexpression of ALD5, PAD1, ATF1 and ATF2 helps Saccharomyces cerevisiae in phenolics conversion and tolerance Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.1.1.102 mitochondrion
-
 Saccharomyces cerevisiae 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.68 coniferyl aldehyde + H2O + NAD+ Saccharomyces cerevisiae
-
 ferulate + NADH + 2 H+
-
 ?
1.2.1.68 coniferyl aldehyde + H2O + NAD+ Saccharomyces cerevisiae CEN.PK 102-3A
-
 ferulate + NADH + 2 H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.68 Saccharomyces cerevisiae
-
-
-
1.2.1.68 Saccharomyces cerevisiae CEN.PK 102-3A
-
-
-
4.1.1.102 Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.68 coniferyl aldehyde + H2O + NAD+
-
 Saccharomyces cerevisiae ferulate + NADH + 2 H+
-
 ?
1.2.1.68 coniferyl aldehyde + H2O + NAD+
-
 Saccharomyces cerevisiae CEN.PK 102-3A ferulate + NADH + 2 H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.68 CALDH
-
 Saccharomyces cerevisiae
4.1.1.102 PAD1
-
 Saccharomyces cerevisiae